Properties: Its contents of albumin, immunoglobulins and coagulation factors is the same as that of fresh frozen plasma, except that the levels of the labile Factors V and VIII are markedly reduced. The fibrinogen concentration is also reduced in comparison to fresh frozen plasma. Should not contain irregular antibodies of clinical significance.

Methods of preparation: Frozen plasma/ cryo-depleted plasma is the by-product of the preparation of cryoprecipitate from fresh frozen plasma.

Storage & Stability: The stability on storage is dependent on the storage temperature. Optimal storage temperature is at -25 degrees celcius or lower. Permitted storage times and temperatures:

(a) 24 months storage at temperatures below -25 degrees celcius.

(b) 3 months storage at temperatures of -18 degrees celcius to -25 degrees celcius.