Index of diseases (A to Z Guide)
   
   

   
   
   
   

Legionnaire's Disease

Legionnaire's disease is an acute bacterial chest disease caused by the bacterium named Legionella pneumophila. The bacterium can be found in water delivery systems and can survive in the warm, moist, air conditioning systems of large buildings including hospitals, hotels and other large establishments, etc. The infection is transmitted through the respiratory system via contaminated aerosols (very small water droplets). Person-to-person spread has not been proved.

Reservoir

The bacterium is water-associated and ubiquitous.

It is often isolated from natural habitats (rivers, creeks, hot springs) and from artificial equipment such as cooling towers associated with air conditioning and industrial processes, and in warm water systems where the temperature is maintained around 43˚C favouring proliferation of the bacteria.

Incubation period

2 - 10 days

Signs and Symptoms

  • Tiredness and weakness
  • Muscle aches and stiffness
  • Fever (generally high fever)
  • Cough: non-productive or coughing blood
  • Shortness of breath
  • Chest Pain
  • Headache
  • Loss of energy
  • General ill feeling (malaise)
  • Abdominal pain
  • Diarrhoea

Diagnosis

Urinary antigen testing for Legionella antibodies carried out locally.

Serum sent abroad for detection of Legionella antibodies.

Treatment

Antibiotic treatment (Erythromycin or Ciprofloxacin) prescribed by medical doctor.

Supportive treatment includes hospitalization for fluid and electrolyte replacement and oxygen administration by mask or by mechanical ventilation, if the respiratory system becomes severely compromised by the infection.

Prognosis

If the patient is treated promptly, the outcome is excellent but if the patient has underlying illness that compromises his/her immune system or appropriate therapy is delayed can result in prolonged hospitalization, complications and sometimes even death.

Control and Prevention

  • Cooling towers of large air conditioning units should be drained when not in use, cleaned with biocides (chlorinating agents) with scales and sediment removed. Chlorination and heating (above 55˚C) of infected source is effective. Important to investigate contacts and find the source of infection. TWO CASES LINKED in time, place or person constitute an outbreak.
  • The Department of Public Health has issued a Code of Practice for the Hospitality Industry.
  • The European Working Group for Legionella infections has set recommendations for Legionnaire’s Disease. (EWGLI Guidelines: http://www.ewgli.org/public_info/publicinfo_europeanguideline_download.asp)
 
 
   
   
 
  Surveillance is the first step towards prevention